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On board a train on its last trip, five people know each other, collide, make friends and solve their personal issues finding out what's really important in life.
Blanca Ferrando is a young woman who became blind at the age of twelve, due to a dramatic fire in which her older sister Beatrice died and which was caused by her violent boyfriend, Sebastian. This tragedy made her develop a very strong sense of justice to the point of pushing her to join the police. Blanca is helped by her most trusted friends: her guide dog Linneo, a female bulldog who protects and comforts her in the most difficult moments, and her beautician friend, Stella. After overcoming her work challenges, she finds herself facing sentimental ones: torn between two men, Inspector Michele Liguori, a man of many secrets, and Nanni, a young cook.
After turning 60, a wealthy woman suddenly falls in love with an attractive and much younger man, but her family raises doubts about his intentions.
Follow brothers Paolo and Ignazio, two small spice merchants who have escaped from a Calabria stuck in the past in search of social redemption. In Sicily they invent a future, turning a small, run-down shop into a flourishing business that young Vincenzo, with his revolutionary ideas, will transform into an economic empire.
Inspector Carlo Guerrieri, a veteran police officer from Rome, finds himself partnered with a rookie who was born in Ivory Coast but raised in the capital.
True crime anthology series about female murderers.
37-year-old Italian-American widow Loretta Castorini believes she is unlucky in love, and so accepts a marriage proposal from her boyfriend Johnny, even though she doesn't love him. When she meets his estranged younger brother Ronny, an emotional and passionate man, she finds herself drawn to him. She tries to resist, but Ronny, who blames his brother for the loss of his hand, has no scruples about aggressively pursuing her while Johnny is out of the country. As Loretta falls for Ronny, she learns that she's not the only one in her family with a secret romance.
Adriano is a middle-aged man living in a dilapidated villa in Tuscany, when a group of young idealistic students arrives to restore the villa's vineyards.
Jack McKee is a doctor with it all: he's successful, he's rich, and he has no problems.... until he is diagnosed with throat cancer. Now that he has seen medicine, hospitals, and doctors from a patient's perspective, he realises that there is more to being a doctor than surgery and prescriptions.