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A young mechanic gets a job with a small airline, which he helps win a mail contract. A rival airline plots to destroy it in order to get the contracts for itself.
An American pilot with a top-secret invention is kidnapped by foreign agents.
The second of a series of four features Monogram made based on the comic strip by Hal Forrest (Universal also used the strip characters in two serials), finds a movie company shooting a war picture at Three Points airport, with Tailspin Tommy Tompkins as a stunt pilot in the film. Tommy is incensed by the complete disregard for human life shown by the film's director, Sheehan, and quits. Sheehan gets a replacement pilot named Earl Martin, who is known as a reckless pilot who will try an aerial stunt for a thrill. He hand Tommy get into a fight when Martin takes Betty Lou Barnes for a ride in a plane that is practically falling apart.
"Tailspin Tommy" Tompkins and "Skeeter" Milligan are training young U. S. Army fliers for the newly-formed 'Sky Patrol,'a branch of the Army Reserves which operates along the borders and coast-lines, on the lookout for smugglers. Carter Meade, whose father is the Colonel in charge of the patrol, has a terror of firing guns and his father insists he conquer this fear. Tommy sends him out on patrol, on orders from Washington D. C., to stop any unfamiliar aircraft. Carter challenges an unmarked amphibian plane, which opens fire on him. Carter, afraid to shoot, bails out as his plane is shot down. Carter is missing, and Tommy and Skeeter are searching for him and the mysterious airplane.
Crooks plot to steal a payroll being shipped by air.
Disaster seems imminent when scientists discover that the planet Mongo is about to crash into Earth. Luckily, heroic young Flash Gordon is on hand to lead an investigative mission into outer space and onto the speedily approaching planet. There, he and his best girl, Dale, who is along for the ride, learn that Ming, the devious ruler of Mongo, has purposely put the planet on a collision course with Earth, and only Flash can stop him.
The daughter of a man who has discovered radium on an African island is befriended by two people whose real goal is to keep the discovery to themselves.
A mysterious plague, the Purple Death, ravages the earth. Dr. Zarkov, investigating in his spaceship, finds a ship from planet Mongo seeding the atmosphere with dust. Sure enough, Ming the Merciless is up to his old tricks. So it's back to Mongo for Flash, Dale, and Zarkov.
Dick Tracy's foe for this serial is the crime boss and Masked Mystery Villain The Spider/The Lame One and his Spider Ring. In the process of various crimes, including using his Flying wing and sound weapon to destroy the Bay Bridge in San Francisco and stealing an experimental "Speed Plane", the Spider captures Dick Tracy's brother, Gordon. The Spider's minion, Dr. Moloch, performs a brain operation on Gordon Tracy to turn him evil, making him secretly part of the Spider Ring and so turning brother against brother.
Janet Allison witnesses Art Holden and his gang hold up the Station Agent. When she identifies Holden to the Sheriff, the Sheriff gives Holden an alibi. Janet and Jim Fentriss then find Holden's secret hideout. When Janet returns the next day to meet Jim, Holden makes her a prisoner and waits in ambush for Jim to arrive.